Aptx4869

aptx4869 is a poison created by the Black Organization. 'APTX' stands for apotoxin, a poison that kills through apoptosis. Apoptosis is the process of programmed cell death. All the information given on how aptx4869 works is technically correct, though it does not explain everything. It was created originally by Shiho Miyano's father, after his death, the research was continued by Shiho, or Sherry as she was called there. It was given to many people, including teen dectective Shinichi Kudo. However, instead of killing Kudo, it showed a rare side effect and shrunk him by ten years, to the size of a six-year-old. He continued to act as a detective in secret, letting the credit to to Kogoro Mouri. After the death of her older sister at teh hands of the Organization, Sherry refused to continue the work any longer. She was sentenced to die, but chose to take the poison instead. The side affect occurred again, and she too became a child again.

aptx4869 is occasionally called 'prototype detective' by the Organization- 'prototype' due to the fact that the research is still incomplete on it, and 'detective' because 4869 is pronounced 'shi-ya-ro-ku' in Japanese, or 'Sherlock'.

There is no known permanent cure for the shrinking affect, though Sherry's research is still in progress. Several temporary antidotes have been made, though the long-term affect is unknown.